aminophylline infusion calculation
Calculate initial dosage using the following equation. Using the infusion strength you know that 1ml would administer 1mg of aminophylline so 225ml would administer 225mg.
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Loading dose Desired concentration - measured concentration volume of distribution Mean volume of distribution.
. 79 Posts Mar 14 2014 ok here goes ordered 300mg500ml have 1000mg20 ml but since all 4 numbers are given Im having a hard time understanding how plugs into the desired over have equation. Precription for IV aminophylline 350mg in 100ml to be given over 30 minutes. Aminophylline is a bronchodilator that is used with other medications to treat sudden worsening of the symptoms of asthma bronchitis or emphysema.
A blood sample should usually be taken 46 hours after an oral dose of a modified-release preparation sampling times may varyconsult local guidelines. First we have to calculate the mcg of the solution. 50kg 23 x Every inch of height over 5ft.
20 to 249 Controlled No adverse reactions are present infusion rate by 25 20 to 249 Controlled Adverse reactions are present Stop infusion for 24 hours subsequent infusion rate at least 25 Adverse reactions symptoms Stop infusion for 24 hours. We would therefore set the infusion rate as 225mlhour 225mg1 where 1 is the strength of the dosage in mlmg. Dose required Bolus Volume Divided by 25 millilitre MAX VOLUME 20 ml Prescription Writtenin Once Only Medicines Section as follows Date Medicine Dose Route Time to be given Signature Aminophylline 250 mg in 10ml solution Bolus Volume.
The volume of solution to be given is calculated as follows. Usual range is 6001600 mgday PO in three to four divided doses. This dose is then divided by the daily frequency of oral theophylline administration.
PEDIATRIC PATIENTS Children are very sensitive to CNS stimulant action of theophylline. Of safety even if current dosage is tolerated. Therefore 1ml of this infusion solution contains 1mg of aminophylline.
Use caution in younger children unable to complain of minor side effects. The nurse needs to calculate how many mLh the IV pump needs to be set at. Plasma-theophylline concentration is measured 5 days after starting oral treatment and at least 3 days after any dose adjustment.
Will rise or fall when the patients clearance is significantly different from the mean population value used to calculate the initial infusion rate. The loading dose calculation must use the formula given below for patients who have taken aminophylline in the last 24 hours. Infusion rates were adjusted based to keep serum theophylline levels within a predefined range in nine studies 21 23 26 28 30 32 34 In two studies 28 32 serum theophylline levels were factored into.
Dose and rate of aminophylline 1 mgml infusion Patient weight - kg use IBW if patient obese Dose mghr Infusion rate mlhr 40 20 20 45 225 225 50 25 25 55 275 275. Therefore in a patient who has received no theophylline in the previous 24 hours a loading dose of intravenous theophylline of 46 mgkg 57 mgkg as aminophylline calculated on the basis of ideal body weight and administered over 30 minutes on average will produce a maximum post-distribution serum concentration of 10 mcgml with a range. Expressed as aminophylline Long-term therapy.
Court Rules That States Medical Malpractice Act Can Apply to Nonpatients. Rectal 500 mg q 68 hr by rectal suppository or retention enema. The authors make no claims of the accuracy of the information contained herein.
1 mL 500 X 50000 so X 100 mcgmL. To find the concentration. -Loading dose Desired concentration - measured concentration volume of distribution.
Therefore a second. Directions for administration For aminophylline. In this case 500ml500mg 1mlmg.
Use ideal body weight for calculations. Intravenous aminophylline therapy was initiated by the ED house staff one to four years postgraduate. Specializes in Med-Surg.
If we have 50 mg in 500 mL by moving our decimal point three spots to the right we have 50000 mcg in 500 mL. The results of therapeutic drug monitoring TDM factored into aminophylline dosage calculations in the majority of studies. -57 mg aminophyllinekg ideal body weight intravenously over 30 minutes For patient who HAVE had theophylline in the past 24 hours based on theophylline serum concentration measurements in mcgmL.
Weight OR IBW if Obese kg Heart Failure Liver Cirrhosis Severe Pulmonary Oedema. Consider if overdose treatment required. Aminophylline infusion rate mghour is multiplied by 24 to yield total daily dose of aminophylline.
And these suggested doses are not a substitute for clinical judgment. Theophylline1 Aminophylline 079 Choledyl064 Target Steady state ngmL range 5-20. 5mgkg 5mg x 70kg 350mg- add to 100ml of infusion fluid and administer over 20 minutes Maintenance Dose.
A calculator used to determine the appropriate dosage of Theophylline. Warnings In an emergency you may not be able to tell caregivers about your health conditions. 500microgramskghour 500micrograms x 70kg per hour 35000microgramshr 35mg per hour Add 500mg aminophylline to 500ml infusion fluid 1mgml concentration Set rate controlled infusion pump at 35ml per hour.
0008 x age in weeks 021 theophylline dosage in mgkghour IV. Aminophylline may also be used for purposes not listed in this medication guide. Reduced doses may be needed in patients with risk factors for reduced theophylline clearance eg cardiac or liver dysfunction renal.
The conventional aminophylline protocol used for group 1 patients consisted of a loading dose of 5 mgkg of body weight administered over 20 minutes followed by an infusion of 04 to 08 mgkgh. - please read Disclaimer Theophylline oral dosing. Aminophylline infusion Find mghr DO mlhr SH gmml Dosage Calculation common icu drips icu iv drips icu drips management.
This dose mgday is then multiplied by 08adjustment for the ethylenediamine component of aminophyllineto yield the total daily dose of theophylline. Seun2014 41 Posts Mar 14 2014 5008hours625 625203125ml imadoll1980 21 Posts Mar 14 2014. The equation for infusion rate calculation is dose stated in prescription milligrams per hour times volume in syringe in millilitres divided by the amount in the syringe in milligrams equals the infusion rate millilitres per hour or.
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